Molecular Biology Module 4: Translation

The TAF1 subunit of TFIID is a histone acetylase. Which of the following is the most likely consequence?

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מיין לפי

Neurons, after they are first born, slowly start to express a neurofilament gene (NF-L) for the first time. The promoter of the NF-L gene is rich in CpG sequences. Which of the following would you expect to observe in the NF-L promoter as the gene becomes increasingly active in neurons?

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Which of the following is directed by transcription activators in eukaryotic cells such as to make DNA more accessible for the transcription machinery.

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מיין לפי

(USMLoid) DNA methylation-induced repression of the Dapk (Death associated protein kinase) gene has been observed in 80% of colorectal carcinomas. Increased methylation of the Dapk gene most likely occurs at which of the following?

1

מיין לפי

Embryonic development and cell differentiation are largely driven by gene regulation. The most common mechanism is at which of the following levels?

1

מיין לפי

The four labelled DNA sequences are bound by proteins with sequence specific DNA-binding domains. Which one most likely binds to a PolII general transcription factor?

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מיין לפי

(USMLoid) The protein encoded the gene ZEB1 was discovered to induce genes causing an Epithelial Mesenchymal Transition (EMT) during breast cancer tumor progression. The gene sequence and protein X-ray crystallography data showed that ZEB1 encodes a Zinc-finger motif. Which of the following is a most likely characteristic of the ZEB1 protein.

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You transfer wildtype E.coli from petri plates containing glucose to petri plates containing lactose. What sequence of events will occur at the lac operon promoter.?

1

מיין לפי

In the context of prokaryotic gene regulation, a repressor is:

1

מיין לפי

Molecular Biology Module 4: Translation

Discuss, Learn and be Happy דיון בשאלות

The TAF1 subunit of TFIID is a histone acetylase. Which of the following is the most likely consequence?

Neurons, after they are first born, slowly start to express a neurofilament gene (NF-L) for the first time. The promoter of the NF-L gene is rich in CpG sequences. Which of the following would you expect to observe in the NF-L promoter as the gene becomes increasingly active in neurons?

Which of the following is directed by transcription activators in eukaryotic cells such as to make DNA more accessible for the transcription machinery.

(USMLoid) DNA methylation-induced repression of the Dapk (Death associated protein kinase) gene has been observed in 80% of colorectal carcinomas. Increased methylation of the Dapk gene most likely occurs at which of the following?

Embryonic development and cell differentiation are largely driven by gene regulation. The most common mechanism is at which of the following levels?

The four labelled DNA sequences are bound by proteins with sequence specific DNA-binding domains. Which one most likely binds to a PolII general transcription factor?

You transfer wildtype E.coli from petri plates containing glucose to petri plates containing lactose. What sequence of events will occur at the lac operon promoter.?

In the context of prokaryotic gene regulation, a repressor is: