ביו-אינפורמטיקה רפואית

In the context of translational bioinformatics, which method is used to identify drug repurposing opportunities?

1

A research team is investigating a disease characterized by overexpression of certain genes. They want to repurpose existing drugs to treat this disease. Which approach would be most effective?

1

Which of the following is a key advantage of using pharmacogenomics in drug repurposing?

1

A scientist is analyzing gene expression data from cancer patients and comparing it to data from patients treated with a variety of drugs. Which outcome would suggest a potential drug candidate for cancer treatment?

1

What is the central dogma of molecular biology?

1

Which type of cell division is responsible for replicating most cells in the human body?

1

שאלה #169342

		Meiosis
		Mitosis
		Binary Fission
		Budding

**מיטוזה** ו**מיוזה** הן שתי דרכים שבהן תאים מתחלקים, אבל יש ביניהן כמה הבדלים חשובים: 1. **מיטוזה (Mitosis):** - קורה ברוב התאים בגוף (כמו תאי עור, שריר, וכו'). - תא אחד מתחלק לשני תאים זהים לגמרי לתא המקורי (כמו שכפול). - יש את אותו מספר כרומוזומים (חומר גנטי) כמו בתא המקורי. - זה קורה כדי לגדול, לשקם רקמות, ולהחליף תאים מתים. 2. **מיוזה (Meiosis):** - קורה רק בתאי מין (ביצית וזרע). - תא אחד מתחלק לארבעה תאים, שכל אחד מהם עם חצי מכמות הכרומוזומים של התא המקורי. - התאים האלה שונים אחד מהשני (ולא זהים כמו במיטוזה). - זה קורה כדי ליצור גיוון גנטי (שינויים בתכונות בין ילדים להורים). **בקצרה:** - **מיטוזה** = שכפול תאים זהים כדי לגדול או לתקן. - **מיוזה** = יצירת תאי מין שונים כדי להעביר תכונות לצאצאים.

מיין לפי

Which of the following statements about DNA is TRUE?

1

שאלה #169344

		It is composed of four nucleotides: A, T, C, and G.
		It forms a triple helix structure.
		It is synthesized by ribosomes.
		It is identical in all human cells.

מיין לפי

Which genetic inheritance pattern requires both alleles to be present for the trait to manifest?

1

שאלה #169345

		Dominant
		Recessive
		Co-dominant
		Incomplete dominance

מיין לפי

Which disease is an example of autosomal recessive inheritance?

1

שאלה #169346

		Cystic Fibrosis
		Huntington's disease
		Hemophilia
		Down syndrome

מיין לפי

Scenario: A mother is a carrier of an X-linked recessive disorder, and the father is unaffected. What is the probability that their son will have the disorder?

1

שאלה #169349

		0%
		25%
		50%
		100%

מיין לפי

		Randomized clinical trials.
		Comparative genomic hybridization.
		Analyzing gene expression profiles to find anti-correlations with disease profiles.
		Using patient-reported outcomes to measure drug efficacy.

		Looking for drugs that show gene expression profiles similar to the disease profile.
		Identifying drugs that induce anti-correlation in gene expression compared to the disease profile.
		Testing all available drugs in clinical trials without prior genetic analysis.
		Focusing only on drugs that were originally developed for a similar disease.

		It reduces the cost and time of drug development.
		It requires no prior knowledge of disease biology.
		It avoids the need for clinical trials altogether.
		It focuses solely on single-gene disorders.

		The drug causes a gene expression profile identical to the cancer profile.
		The drug alters gene expression in a way that correlates positively with cancer progression.
		The drug shows no effect on gene expression profiles.
		The drug induces a gene expression profile that is anti-correlated with the cancer profile.

		RNA → DNA → Protein
		RNA → Protein → DNA
		Protein → RNA → DNA
		DNA → RNA → Protein

ביו-אינפורמטיקה רפואית

Discuss, Learn and be Happy דיון בשאלות

In the context of translational bioinformatics, which method is used to identify drug repurposing opportunities?

שאלה #169334

A research team is investigating a disease characterized by overexpression of certain genes. They want to repurpose existing drugs to treat this disease. Which approach would be most effective?

שאלה #169335

Which of the following is a key advantage of using pharmacogenomics in drug repurposing?

שאלה #169336

A scientist is analyzing gene expression data from cancer patients and comparing it to data from patients treated with a variety of drugs. Which outcome would suggest a potential drug candidate for cancer treatment?

שאלה #169337

What is the central dogma of molecular biology?

שאלה #169340

Which type of cell division is responsible for replicating most cells in the human body?

שאלה #169342

Which of the following statements about DNA is TRUE?

שאלה #169344

Which genetic inheritance pattern requires both alleles to be present for the trait to manifest?

שאלה #169345

Which disease is an example of autosomal recessive inheritance?

שאלה #169346

Scenario: A mother is a carrier of an X-linked recessive disorder, and the father is unaffected. What is the probability that their son will have the disorder?

שאלה #169349

ביו-אינפורמטיקה רפואית

Discuss, Learn and be Happy דיון בשאלות

In the context of translational bioinformatics, which method is used to identify drug repurposing opportunities?

A research team is investigating a disease characterized by overexpression of certain genes. They want to repurpose existing drugs to treat this disease. Which approach would be most effective?

Which of the following is a key advantage of using pharmacogenomics in drug repurposing?

A scientist is analyzing gene expression data from cancer patients and comparing it to data from patients treated with a variety of drugs. Which outcome would suggest a potential drug candidate for cancer treatment?

What is the central dogma of molecular biology?

Which type of cell division is responsible for replicating most cells in the human body?

Which of the following statements about DNA is TRUE?

Which genetic inheritance pattern requires both alleles to be present for the trait to manifest?

Which disease is an example of autosomal recessive inheritance?

Scenario: A mother is a carrier of an X-linked recessive disorder, and the father is unaffected. What is the probability that their son will have the disorder?

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