שאלה | Using recombinant DNA technology to insert a 500,000 bp fragment of human genomic DNA into the genome of E. coli will likely

Using recombinant DNA technology to insert a 500,000 bp fragment of human genomic DNA into the genome of E. coli will likely

		cause uncontrolled DNA replication due to the multiple origins of replication added.
		dramatically increase the time needed to replicate the E.coli genome due to the formation of nucleosomes.
		kill the bacteria due to the production of a large number of foreign gene products.
		slightly increase the time needed to replicate the E.coli genome due to the extra amount of DNA
		stop DNA replication due to the inability of the prokaryotic replication machinery to recognize methylated C.