The VHL gene is often mutated in people suffering from von Hippel-Lindau (VHL) disease. The VHL protein is found in a ubiquitin-ligase complex that targets the transcription factor Hypoxia Inducible Factor 1 (HIF-1). In VHL patients HIF-1 is not targeted for destruction by the ubiquitination pathway. Which of the following genes will most likely show increased gene expression as a result?
The VHL gene is often mutated in people suffering from von Hippel-Lindau (VHL) disease. The VHL protein is found in a ubiquitin-ligase complex that targets the transcription factor Hypoxia Inducible Factor 1 (HIF-1). In VHL patients HIF-1 is not targeted for destruction by the ubiquitination pathway. Which of the following genes will most likely show increased gene expression as a result?
* השאלה נוספה בתאריך: 27-12-2020