שאלה | Neurons, after they are first born, slowly start to express a neurofilament gene (NF-L) for the first time. The promoter of the NF-L gene is rich in CpG sequences. Which of the following would you expect to observe in the NF-L promoter as the gene becomes increasingly active in neurons?

Neurons, after they are first born, slowly start to express a neurofilament gene (NF-L) for the first time. The promoter of the NF-L gene is rich in CpG sequences. Which of the following would you expect to observe in the NF-L promoter as the gene becomes increasingly active in neurons?

		1. Increased binding of Repressor proteins to the NF-L promoter, leading to increased methylation of C in the sequence CpG.
		2. Increased recruitment of histone deacetylase (HDAC) to the promoter, leading to a decrease in the methylation of C in sequences other than CpG.
		3. Loss of methylation of C in sequences other than CpG.
		4. Increased recruitment of histone deacetylase (HDAC) to the promoter, leading to heterochromatinization of the NF-L gene.
		5. Loss of methylation of C in the sequence CpG.